IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
نویسندگان
چکیده
منابع مشابه
IL-17+Foxp3+ T cells: an intermediate differentiation stage between Th17 cells and regulatory T cells.
Foxp3(+) Tregs have been known as a major regulator of immune homeostasis through their immunosuppressive function. Th17 lineage is a CD4(+) T cell subset that exerts its function by secreting proinflammatory cytokines and protecting host against microbial infections. The altered ratio between Foxp3(+) Tregs and Th17 cells plays an important role in the pathogenesis of immune-related diseases. ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2009
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0812530106